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Johnson & Johnson HIV vaccine trial fails

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Posted By: Ribicon, 9/1/2021 9:11:58 AM

An HIV vaccine candidate manufactured by Johnson & Johnson failed to provide sufficient protection against infection, the company announced Tuesday, the latest blow to the HIV vaccination effort.(Snip)The study enrolled approximately 2,600 young women across five countries in sub-Saharan Africa, a region where women and girls accounted for 63 percent of all new HIV infections in 2020. Participants were randomly selected to receive either the vaccine or a placebo, and researchers found the vaccine's efficacy was only about 25 percent, which was not statistically significant. The investigational HIV vaccine was manufactured using a strain of common-cold virus engineered to not cause illness, the same basic technology

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An HIV vaccine using the same technology as their coronavirus vaccine left 75% of the subjects catching the HIV anyway. They forgot to claim that the vaccine works great, except that there's a new variant of HIV and more boosters are needed.

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Reply 1 - Posted by: Come And Take It 9/1/2021 9:23:49 AM (No. 900469)
Johnson and Johnson should stick to making things like baby powder...oh wait...
12 people like this.

Reply 2 - Posted by: DVC 9/1/2021 10:23:58 AM (No. 900556)
And since the other ones don't protect you either, why are people taking these shots?
7 people like this.

Reply 3 - Posted by: voxpopuli 9/1/2021 10:32:00 AM (No. 900571)
WOW.. this earth shattering news must be REALLY important! oh.. stock is down 40 CENTS.. must be a lot of skeptical people out there that don't care about the OLD shiny hiv object
1 person likes this.

Reply 4 - Posted by: Californian 9/1/2021 10:58:26 AM (No. 900593)
Sad but that's how real science works. They had a hypothesis. They tested it. It failed. Information learned will go towards improving and trying agsin. The JnJ vaccine is a traditional style vaccine, the same science used to wipe out small pox and many other nasty bugs. It is not the same as the mRNA Pfizer shot. It also hasn't killed 10,000 people like Pfizer has. I look forward to further advances in medical science.
4 people like this.

Reply 5 - Posted by: columba 9/1/2021 11:11:21 AM (No. 900609)
There is already in place a vaccine that works. It's called faithful marriage between a man and a woman.
3 people like this.

Reply 6 - Posted by: Kate318 9/1/2021 11:12:17 AM (No. 900610)
FTA: The investigational HIV vaccine was manufactured using a strain of common-cold virus engineered to not cause illness, the same basic technology as Johnson & Johnson's coronavirus vaccine. There is so much wrong in this sentence, I don’t know where to begin.
2 people like this.

Reply 7 - Posted by: davew 9/1/2021 1:07:20 PM (No. 900757)
HIV vaccine research is being rapidly eclipsed by the emerging science of exosome communications between cells like CD4 T-lymphocytes and viral particles. HIV is able to disable the immune system by infecting T-cells and using them to produce more virus. Exosomes are small vessels of RNA and other proteins that are used by all the cells of the body to communicate coordinated responses like immunity. They are like packets used across the internet but are chemical rather than electrical. HIV behaves like an exosome to infect immune cells that are normally able to destroy them like a virus on a computer that can modify the operating system to do harm. What the research is learning is how to create exosomes that enable cells to detect HIV and defeat it like anti-virus software by activating the normal gene immune response to the HIV virus before it ever gets started. The use of exosomes in medicine may well be even more powerful to future medicine than gene editing technologies like CRISP/Cas9 that only address single gene related diseases at this point. Right now only a few small non-public companies are working with the big drug companies (including J&J) to develop game changing exosome based therapies but some of these may get to the IPO stage and would be an interesting speculative investment for informed investors.
1 person likes this.

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