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Modified Cold Sore Virus Shrinks
Melanoma Tumors, Amgen Says

Forbes, by Matthew Herper

Original Article

Posted By:earlybird, 3/21/2013 12:29:47 PM

A genetically modified version of herpes simplex virus type 1, the same virus that causes cold sores, shrank tumors of the deadly skin cancer melanoma in a clinical trial, according to Amgen, which is developing the experimental cancer treatment. Patients in the trial were in the late stages of the disease, and were either being treated with a drug called GM-CSF or the new virus. Sixteen percent of the patients in the group that got the virus, known as talimogene laherparepvec, saw their tumors shrink completely or partially for at least six months.

      


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Reply 1 - Posted by: Mother of AL, 3/21/2013 12:47:13 PM     (No. 9236924)

This is good. I have had a malignant melanoma, but it was caught early enough that I am at 12 years survival. It was a result of many years spent in the sun, to get a "great tan". Silly..now that I have some age on me. Thanks for posting.....I was through, but one more thought occurred to me. This treatment will probably be expensive, so 0´s death panels will get to decide who gets the treatment.

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Reply 2 - Posted by: dubyarules, 3/21/2013 1:40:34 PM     (No. 9237041)

Melanoma can be a very deadly disease. Get a skin exam by a dermatologist at least yearly.

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Reply 3 - Posted by: earlybird, 3/21/2013 2:26:36 PM     (No. 9237117)

In between any skin exams, Google "Melanoma", have a read, and keep an eye on any skin lesions.

Many of us got too much sun. Many still do. Squamous cell carcinoma can be serious if not caught early. Melanoma can be a death sentence, and an ugly one. Both are relatively simple to manage if people are aware and pay attention to changes in their bodies.

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Reply 4 - Posted by: thelmalou, 3/21/2013 2:44:29 PM     (No. 9237147)

I get the feeling we´re on the cusp of several radical medical breakthroughs. Esp. with kids like the one who discovered the test that detects pancreatic and other cancers early for like $3 OTC, and the kid who discovered the gel which stops bleeding almost immediately. Fascinating.


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Reply 5 - Posted by: woofwoofwoof, 3/21/2013 7:38:09 PM     (No. 9237565)

Modified, hmm? Amgen is big on making trivial modifications, IOW I wonder if the "wild" virus already has this property?


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DOWNTOWN LOS ANGELES -- New details are surfacing about the role Archbishop Roger Mahony played in the investigation of sexual abuse by Catholic priests. When Los Angeles police were investigating allegations of child abuse by a Roman Catholic priest in 1988, they asked for a list of altar boys at the last parish where the priest worked. According to a deposition made public on Wednesday and obtained by the Associated Press, Mahony told a subordinate not to give the list, saying he didn´t want to scare the boys who knew nothing about the investigation. Detectives investigating allegations against Nicolas Aguilar

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SOCHI, Russia -- T.J. Oshie scored four times in the shootout and got the winner in the eighth round, leading the United States past Russia 3-2 Saturday in the thrilling revival of a classic Olympic hockey rivalry. Cam Fowler and Joe Pavelski scored in regulation for the Americans in the marquee game of the preliminary round. Jonathan Quick made 29 saves and stopped five attempts in the shootout. International rules allow the same player to take multiple shots after the first three rounds of a shootout, and U.S. coach Dan Bylsma leaned on Oshie, one of the NHL´s shootout specialists.

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